Yesterday I blogged about an interesting study related to chronic obstructive pulmonary disease (COPD).
At the end of the New England Journal of Medicine article, I started looking at the list of potential conflicts of interest. But I had to give up after a few lines. I send kudos to the researchers for really laying their conflicts on the table.
One of my eyebrows always raise when a researcher says he or she has no potential conflicts of interest to declare prior to a presentation about their area of expertise or in a journal article.
These researchers, though, tell us so much about potential conflicts that its likely many people won't make it all the way through the list. Check this out (and see if you can read the whole thing — I broke it into bullet points to make it easier to digest):
• Dr. Albert reports receiving consulting fees from Gilead Sciences, fees for expert testimony from the Bruce Fagel Law Firm, and royalties from Elsevier, and being named on a patent pending for a device that provides continuous monitoring of the elevation of the head of the bed (Denver Health and the University of Colorado)
• Dr. Casaburi, receiving payment for service on the advisory boards of Novartis Pharmaceuticals and Forest Pharmaceuticals, consulting fees from Theratechnologies, Breathe Technologies, Medtronic Spinal and Biologics, Boehringer Ingelheim, Philips Respironics, Novartis, and Actelion Pharmaceuticals, lecture fees from Boehringer Ingelheim, AstraZeneca, and Pfizer, holding stock in Inogen, and receiving grant support from Novartis, Roche, Boehringer Ingelheim, Osiris Therapeutics, Forest Pharmaceuticals, and GlaxoSmithKline, Breathe Technologies (pending), and Theratechnologies (pending)
• Dr. Cooper, receiving fees for expert testimony from Watkins, Louri, Roll and Change; Lawrence R. Dry & Associates; Starnes Davis Florie LLP; Walker, Tipps & Malone PLC; Moore, Ingram Johnson & Steele; and Farris, Riley & Pitt, LLP; and grant support from GlaxoSmithKline and Novartis
• Dr. Criner, receiving consulting fees from Phillips Pharmaceuticals, GlaxoSmithKline, Uptake Medical, and Dey, grant support from Philips Respironics, GlaxoSmithKline, Boehringer Ingelheim, Novartis, and AstraZeneca, and royalties from Springer
• Dr. Curtis, receiving grant support from Boehringer Ingelheim
• Dr. Dransfield, receiving consulting fees from GlaxoSmithKline, Boehringer Ingelheim, and Forest Pharmaceuticals, grant support from GlaxoSmithKline, Boehringer Ingelheim, and Boston Scientific, and lecture fees from GlaxoSmithKline and Boehringer Ingelheim
• Dr. Han, receiving payment for service on the advisory boards of CSL Behring, GlaxoSmithKline, and Boehringer Ingelheim, consulting fees from Genentech and Novartis, lecture fees from GlaxoSmithKline, CSL Behring, Boehringer Ingelheim, and Pfizer, royalties from UpToDate, and meeting expenses from AstraZeneca
• Dr. Madinger, receiving honoraria in conjunction with the Merck Study Monitoring Antimicrobial Resistance Trends (SMART), the JMI Laboratories Sentry study, and the Eurofins Medinet Trust study
• Dr. Make, receiving payment for service on the advisory boards of Forest Pharmaceuticals, AstraZeneca, Novartis, Dey, Nycomed, Philips Respironics, Schering-Plough (now Merck), SeQual, Embryon, Boehringer Ingelheim, Pfizer, and GlaxoSmithKline, consulting fees from Astellas Pharma, Talecris Biotherapeutics, and Chiesi Pharmaceuticals, lecture fees from GlaxoSmithKline, Boehringer Ingelheim, Pfizer, and Forest Pharmaceuticals, payment for manuscript preparation from AstraZeneca, payment for video presentation preparation from Boehringer Ingelheim and Pfizer, payment for document reviews from Spiration, and grant support from AstraZeneca, GlaxoSmithKline, Pfizer, Nabi Biopharmaceuticals, Boehringer Ingelheim, and Sunovion
• Dr. Martinez, receiving payment for service on the advisory boards of GlaxoSmithKline, MedImmune–Astra Zeneca, Merck, Pearl Therapeutics, Novartis, UBC, Mpex Pharmaceuticals and Ikaria, consulting fees from Forest–Almirall, Boehringer Ingelheim, Nycomed–Forest, Roche, Bayer, Schering-Plough (Merck), HLS, Talecris Biotherapeutics, Comgeniz, fb Communications, BoomComm, Actelion Pharmaceuticals, Elan, Genzyme, Quark Pharmaceuticals, Merck, Pfizer, and Sanofi-Aventis, royalties from Associates in Medical Marketing and Castle Connolly, lecture fees from GlaxoSmithKline, National Association for Continuing Education, Med-Ed, Potomac Pharma, Pfizer, Boehringer Ingelheim, Schering-Plough (Merck), Vox Medica, WebMD, Epocrates, AstraZeneca, and Altana–Nycomed, payment for development of educational presentations for HIT Global and UpToDate, and grant support from Boehringer Ingelheim, Gilead, Johnson & Johnson–Centocor Ortho Biotech, and Actelion Pharmaceuticals
• Dr. McEvoy, receiving grant support from Boston Scientific and GlaxoSmithKline and lecture fees from Boehringer Ingelheim and GlaxoSmithKline
• Dr. Niewoehner, receiving consulting fees from Boehringer Ingelheim, AstraZeneca, GlaxoSmithKline, Forest Research, Merck, Sanofi-Aventis, Bayer Schering Pharma, Nycomed, ProtAffin, and Pfizer
• Dr. Porszasz, receiving consulting fees from Breathe Technologies, Boehringer Ingelheim, Novartis, and Forest Pharmaceuticals, and grant support from Boehringer Ingelheim, Forest Pharmaceuticals, Breathe Technologies (pending), and Novartis
• Dr. Price, receiving consulting fees from Astellas Pharma, Cubist Pharmaceuticals, and Merck, providing expert testimony on transmission of hospital-associated infections, management of musculoskeletal infections, aminoglycoside toxicity, and diagnosis of infection, receiving grant support from MicroPhage, Cubist Pharmaceuticals, Quintiles, Sanofi Pasteur, BioCryst Pharmaceuticals, and Accelr8 Technology, and lecture fees from Robert Michael (a CME vendor), Cubist Pharmaceuticals, and Baxter Healthcare
• Dr. Scanlon, receiving grant support from Altana, Boehringer Ingelheim, Dey, Forest Pharmaceuticals, GlaxoSmithKline, Novartis, and Pfizer and royalties from Lippincott Williams & Wilkins and Wolters Kluwer
• Dr. Sciurba, receiving consulting fees from Boehringer Ingelheim, AstraZeneca, and GlaxoSmithKline and grant support from Pfizer and GlaxoSmithKline
• Dr. Washko, receiving consulting fees from MedImmune and Spiration and being married to an employee of Merck Research Laboratories Division of Clinical Pharmacology
• Dr. Woodruff, receiving consulting fees from MedImmune, grant support from Genentech, and being a coinventor on a patent held jointly by his institution and Genentech.
No other potential conflict of interest relevant to this article was reported.
Did you make it all the way through? I'm wondering if anyone is studying how many conflicts get reported nowadays versus those that were reported, say, a few years ago. It's interesting to consider the ethical concerns those who push for more transparency might bring to the table but also to recognize the simple use of space that is now being devoted to such lists in the scientific journals.
Pulse on Health
By Jeff Hansel, member Association of Health Care Journalists
Health Reporter for the PostBulletin.com, 18 1st Ave. S.E. in Rochester, Minnesota 55904
Twitter Hansel's Pulse: @Jeff Hansel